pyoderma gangrenosum-like lesions, Sweet’s syndrome-like lesions, cutaneous vasculitis lesions which may present as palpable purpura, bullous or necrotizing lesions, facial and acral vesicopustules, extragenital ulcers and superficial thrombophlebitis. Skin involvement is a major feature of BD occurring in % of patients. In a recent. Behçet's syndrome is a rare multisystem inflammatory disorder characterized by ulcers affecting the mouth and genitals, various skin lesions, and abnormalities affecting the eyes. Symptoms include mucous membrane lesions of the mouth (canker sores) and genitals (ulcers) that tend to disappear and recur spontaneously.
Cutaneous manifestations of Behcet's Disease generally occur in % of patients. Erythema nodosum, an inflammation occurring in the fatty layer of the subcutaneous tissue, causes red tender nodules to form under the skin. These nodules frequently ulcerate, unlike the erythema nodosum lesions which occur with other diseases. For instance, the erythema nodosum-like lesions of Behçet’s disease are clinically indistinguishable from those that occur in association with streptococcal infection, sarcoidosis, inflammatory bowel disease, rheumatoid arthritis or no underlying disease.
Skin lesions occurred in 64% of Behcet's patients from the United States and are often essential to meet diagnostic disease criteria. The ISG Criteria (Table 1) recognize erythema nodosum, pseudofolliculitis, papulopustular lesions, or acneiform nodules for the diagnosis. Histopathologic findings in lesions of erythema nodosum are those of a.