Macrophage activation syndrome (MAS) is a potentially lethal complication of chronic rheumatological conditions like ankylosing spondylitis, rheumatoid arthritis, and adult-onset Still's disease (AOSD). It is a multisystem inflammatory syndrome caused by immense cytokine release from activated lymphocytes and virginxx.xyz: Madeeha Gulzar, Ali Sabir, Muhammad Afzal Hamdani, Asma Saadia. Macrophage activation syndrome (MAS) has been reported up to 15% of AOSD patients and it is considered to be the most severe complication of the disease being characterised by high mortality rate. During AOSD, laboratory tests reflect the systemic inflammatory process showing high levels of erythrocyte sedimentation rate and C-reactive virginxx.xyz by:
Nov 21, · Macrophage activation syndrome (MAS) is a life-threatening complication of rheumatic disease that, for unknown reasons, occurs much more frequently in individuals with systemic juvenile idiopathic. Adult Onset Still’s disease (AOSD) is a systemic inflammatory disorder of unknown aetiology. Rarely, it may be complicated by Macrophage Activation Syndrome (MAS), a multisystem inflammatory syndrome caused by massive cytokine .
Mar 26, · Stern A, Riley R, Buckley L. Worsening of macrophage activation syndrome in a patient with adult onset Still’s disease after initiation of etanercept therapy. J Clin Rheumatol. ;7(4)–Cited by: 2. Here, we present a year-old female patient with adult-onset Still's disease (AOSD) who was newly diagnosed in the setting of secondary macrophage activation syndrome (MAS), a rare, life-threatening inflammatory disease with 50% mortality due to multi-organ failure. She met the diagnostic criteria Cited by: 1.